Article
Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases.
Rheumatology (Oxford, England) - 1 Jul 2010
Maiti Amit K, Kim-Howard Xana, Viswanathan Parvathi, Guillén Laura, Qian Xiaoxia, Rojas-Villarraga Adriana, Sun Celi, Cañas Carlos, Tobón Gabriel J, Matsuda Koichi, Shen Nan, Cherñavsky Alejandra C, Anaya Juan-Manuel, Nath Swapan K
Abstract excerpt
OBJECTIVES: Recently, a non-synonymous (Gly307Ser) variant, rs763361, in the CD226 gene was shown to be associated with multiple autoimmune diseases (ADs) in European Caucasian populations. However, shared autoimmunity with CD226 has not been evaluated in non-European populations. The aim of the present study is to assess the association of this single nucleotide polymorphism (SNP) with ADs in non-European...
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