Article
Phenotypical and ultrastructural features of Oct4-positive cells in the adult mouse lung.
Journal of cellular and molecular medicine - 1 Jul 2014
Galiger Celimene, Kostin Sawa, Golec Anita, Ahlbrecht Katrin, Becker Sven, Gherghiceanu Mihaela, Popescu Laurentiu M, Morty Rory E, Seeger Werner, Voswinckel Robert
Abstract excerpt
Octamer binding trascription factor 4 (Oct4) is a transcription factor of POU family specifically expressed in embryonic stem cells (ESCs). A role for maintaining pluripotency and self-renewal of ESCs is assigned to Oct4 as a pluripotency marker. Oct4 can also be detected in adult stem cells such as bone marrow-derived mesenchymal stem cells. Several studies suggest a role for Oct4 in sustaining self-renewal...
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