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Dental Pulp Stem Cells Differentiation Reveals New Insights in Oct4A Dynamics

23 Jul 2012

Abstract excerpt

Although the role played by the core transcription factor network, which includes c-Myc, Klf4, Nanog, and Oct4, in the maintenance of embryonic stem cell (ES) pluripotency and in the reprogramming of adult cells is well established, its persistence and function in adult stem cells are still debated. To verify its persistence and clarify the role played by these molecules in adult stem cell function, we...

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PMID: 22844522
DOI: 10.1371/journal.pone.0041774

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