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Article

A nonapoptotic role for CASP2/caspase 2

4 Apr 2014

Abstract excerpt

CASP2/caspase 2 plays a role in aging, neurodegeneration, and cancer. The contributions of CASP2 have been attributed to its regulatory role in apoptotic and nonapoptotic processes including the cell cycle, DNA repair, lipid biosynthesis, and regulation of oxidant levels in the cells. Previously, our lab demonstrated CASP2-mediated modulation of autophagy during oxidative stress. Here we report the novel finding...

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Share to Autophagy in Disease and Therapy
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PMID: 24879153
DOI: 10.4161/auto.28528

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