Article
Human CD4+ T cell responses to the dog major allergen Can f 1 and its human homologue tear lipocalin resemble each other.
PloS one - 1 Jan 2014
Liukko Aino L K, Kinnunen Tuure T, Rytkönen-Nissinen Marja A, Kailaanmäki Anssi H T, Randell Jukka T, Maillère Bernard, Virtanen Tuomas I
Abstract excerpt
Lipocalin allergens form a notable group of proteins, as they contain most of the significant respiratory allergens from mammals. The basis for the allergenic capacity of allergens in the lipocalin family, that is, the development of T-helper type 2 immunity against them, is still unresolved. As immunogenicity has been proposed to be a decisive feature of allergens, the purpose of this work was to examine human...
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