Article
Common variants in FAN1, located in 15q13.3, confer risk for schizophrenia and bipolar disorder in Han Chinese.
Progress in neuro-psychopharmacology & biological psychiatry - 20 Dec 2020
Jian Xuemin, Chen Jianhua, Li Zhiqiang, Fahira Aamir, Shao Weihuan, Zhou Juan, Wang Ke, Wen Yanqin, Zhang Jinmai, Yang Qiangzhen, Pan Dun, Wang Zhuo, Shi Yongyong
Abstract excerpt
Multiple genetic risk factors have been associated with psychiatric disorders which provides the genetic insight to these disorders; however, the etiology of these disorders is still elusive. 15q13.3 was previously associated with schizophrenia, bipolar and other neurodevelopmental disorders. Whereas, the FAN1 which encodes the Fanconi anemia associated nuclease 1 was suggested to be causal gene for 15q13.3...
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