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Mitochondrial Quality Control Strategies: Potential Therapeutic Targets for Neurodegenerative Diseases?

12 Nov 2021

Abstract excerpt

Many lines of evidence have indicated the therapeutic potential of rescuing mitochondrial integrity by targeting specific mitochondrial quality control pathways in neurodegenerative diseases, such as Parkinson's disease, Huntington's disease, and Alzheimer's disease. In addition to ATP synthesis, mitochondria are critical regulators of ROS production, lipid metabolism, calcium buffering, and cell death. The...

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Alzheimer's disease research and treatments
Autophagy in Disease and Therapy
Mitochondrial Function and Pathology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34867159
DOI: 10.3389/fnins.2021.746873

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