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Article

Association between recent acetaminophen use and asthma: modification by polymorphism at TLR4.

Journal of Korean medical science - 1 May 2014

Lee Seung-Hwa, Kang Mi-Jin, Yu Ho-Sung, Hong Kyungmo, Jung Young-Ho, Kim Hyung-Young, Seo Ju-Hee, Kwon Ji-Won, Kim Byoung-Ju, Kim Ha-Jung, Kim Young-Joon, Kim Hee-Suk, Kim Hyo Bin, Park Kang Seo, Lee So-Yeon, Hong Soo-Jong

Abstract excerpt

The risk of asthma has been increasing in parallel with use of acetaminophen, which is a potential source of oxidative stress. Toll-like receptor 4 (TLR4) plays a critical role not only in innate immunity, but also in mediating reactive oxygen species induced inflammation. Therefore, we investigated associations between acetaminophen usage and TLR4 polymorphism on asthma and bronchial hyperresponsiveness (BHR)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24851022
DOI: 10.3346/jkms.2014.29.5.662
PMCID: PMC4024959

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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