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The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach

19 Aug 2017

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is an age and smoking related progressive, pulmonary disorder presenting with poorly reversible airflow limitation as a result of chronic bronchitis and emphysema. The prevalence, disease burden for the individual, and mortality of COPD continues to increase, whereas no effective treatment strategies are available. For many years now, a combination of bronchodilators...

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PMID: 28830839
DOI: 10.1016/j.pharmthera.2017.08.007

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