VE1 antibody immunoreactivity in normal anterior pituitary and adrenal cortex without detectable BRAF V600E mutations.

Abstract excerpt

OBJECTIVES: The VE1 monoclonal antibody was developed to recognize the V600E mutation in BRAF, which is found in various tumors. METHODS: We report that the VE1 antibody stains normal anterior pituitary gland and adrenal cortex, which lack detectable BRAF V600E mutations. RESULTS: Staining with the VE1 antibody was seen in the adenohypophysis and correlated well with adrenocorticotropic hormone (ACTH)-positive...

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