Article
N-acetylglucosamine deacetylases modulate the anchoring of the gamma-glutamyl capsule to the cell wall of Bacillus anthracis.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jun 2014
Candela Thomas, Balomenou Stavroula, Aucher Willy, Bouriotis Vassilis, Simore Jean-Pierre, Fouet Agnes, Boneca Ivo G
Abstract excerpt
Bacillus anthracis has a complex cell wall structure composed of a peptidoglycan (PG) layer to which major structures are anchored such as a neutral polysaccharide, an S-layer, and a poly-γ-D-glutamate (PDGA) capsule. Many of these structures have central roles in the biology of B. anthracis, particularly, in virulence. However, little attention has been devoted to structurally study the PG and how it is modified...
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