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Article

Diagnosis and management of differentiated thyroid cancer using molecular biology.

The Laryngoscope - 1 Apr 2013

Witt Robert L, Ferris Robert L, Pribitkin Edmund A, Sherman Steven I, Steward David L, Nikiforov Yuri E

Abstract excerpt

OBJECTIVES/HYPOTHESIS: To define molecular biology in clinical practice for diagnosis, surgical management, and prognostication of differentiated thyroid cancer. DATA SOURCES: Ovid Medline 2006-2012 REVIEW METHODS: Manuscripts with clinical correlates. RESULTS: Papillary thyroid carcinomas harbor point mutations of the BRAF and RAS genes or RET/PTC rearrangements, all of which activate the mitogen-activated...

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Carcinoma, Papillary
Adenocarcinoma, Follicular
Carcinoma
PAX8 gene
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thyroid Cancer, Papillary

Thyroid Neoplasms

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Identifiers

PMID: 23404751
DOI: 10.1002/lary.23838

Genes

BRAF
PAX8
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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