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Article

CD4 <sup>+</sup> T-Cell Help Enhances NK Cell Function following Therapeutic HIV-1 Vaccination

15 May 2014

Abstract excerpt

UNLABELLED: Increasing data suggest that NK cells can mediate antiviral activity in HIV-1-infected humans, and as such, novel approaches harnessing the anti-HIV-1 function of both T cells and NK cells represent attractive options to improve future HIV-1 immunotherapies. Chronic progressive HIV-1 infection has been associated with a loss of CD4(+) T helper cell function and with the accumulation of anergic NK...

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PMID: 24829350
DOI: 10.1128/jvi.00924-14

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