Article
Characterization of microtubule-binding and dimerization activity of Giardia lamblia end-binding 1 protein.
PloS one - 1 Jan 2014
Kim Juri, Nagami Sara, Lee Kyu-Ho, Park Soon-Jung
Abstract excerpt
End-binding 1 (EB1) proteins are evolutionarily conserved components of microtubule (MT) plus-end tracking protein that regulate MT dynamics. Giardia lamblia, with two nuclei and cytoskeletal structures, requires accurate MT distribution for division. In this study, we show that a single EB1 homolog gene of G. lamblia regulates MT dynamics in mitosis. The haemagglutinin-tagged G. lamblia EB1 (GlEB1) localizes to...
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