Article
Knockdown of Inner Arm Protein IC138 in Trypanosoma brucei Causes Defective Motility and Flagellar Detachment.
PloS one - 1 Jan 2015
Wilson Corinne S, Chang Alex J, Greene Rebecca, Machado Sulynn, Parsons Matthew W, Takats Taylor A, Zambetti Luke J, Springer Amy L
Abstract excerpt
Motility in the protozoan parasite Trypanosoma brucei is conferred by a single flagellum, attached alongside the cell, which moves the cell forward using a beat that is generated from tip-to-base. We are interested in characterizing components that regulate flagellar beating, in this study we extend the characterization of TbIC138, the ortholog of a dynein intermediate chain that regulates axonemal inner arm...
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