Article
Genomics-inspired discovery of natural products.
Current opinion in chemical biology - 1 Feb 2011
Winter Jaclyn M, Behnken Swantje, Hertweck Christian
Abstract excerpt
The massive surge in genome sequencing projects has opened our eyes to the overlooked biosynthetic potential and metabolic diversity of microorganisms. While traditional approaches have been successful at identifying many useful therapeutic agents from these organisms, new tactics are needed in order to exploit their true biosynthetic potential. Several genomics-inspired strategies have been successful in...
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