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Article

Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease.

Human molecular genetics - 15 Sept 2014

Winner Beate, Marchetto Maria C, Winkler Jürgen, Gage Fred H

Abstract excerpt

While motor neuron diseases are currently incurable, induced pluripotent stem cell research has uncovered some disease-relevant phenotypes. We will discuss strategies to model different aspects of motor neuron disease and the specific neurons involved in the disease. We will then describe recent progress to investigate common forms of motor neuron disease: amyotrophic lateral sclerosis, hereditary spastic...

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Identifiers

PMID: 24821704
DOI: 10.1093/hmg/ddu205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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