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Article

MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome.

Scandinavian journal of clinical and laboratory investigation - 1 Sept 2014

Hedley Paula L, Carlsen Anting L, Christiansen Kasper M, Kanters Jørgen K, Behr Elijah R, Corfield Valerie A, Christiansen Michael

Abstract excerpt

Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias. Using DNA screening and sequencing methods, over 700 different LQTS-causing mutations have been identified in 13 genes worldwide. Despite this, the genetic cause of 30-50% of LQTS is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24809446
DOI: 10.3109/00365513.2014.905696
PMCID: PMC4196592

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MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome.PMID 24809446Read ↗

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