Common genetic polymorphisms in pre-microRNAs were associated with increased risk of dilated cardiomyopathy.

doi:10.1016/j.cca.2010.05.010

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Article

Common genetic polymorphisms in pre-microRNAs were associated with increased risk of dilated cardiomyopathy.

Clinica chimica acta; international journal of clinical chemistry - 6 Sept 2010

Zhou Bin, Rao Li, Peng Ying, Wang Yanyun, Chen Yu, Song Yaping, Zhang Lin

Abstract excerpt

BACKGROUND: Common single nucleotide polymorphisms (SNPs) in pre-microRNAs may change their property through altering microRNAs (miRNAs) expression and/or maturation, resulting diverse functional consequences. We conducted a pilot study to test whether SNPs in pre-microRNAs were associated with dilated cardiomyopathy (DCM). METHODS: Genotypes of 3 SNPs in pre-miRNAs (has-mir-196a2 rs11614913 C/T, hsa-mir-499...

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PMID: 20488170
DOI: 10.1016/j.cca.2010.05.010

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