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Article

Adherens junctional associated protein-1: a novel 1p36 tumor suppressor candidate in gliomas (Review).

International journal of oncology - 1 Jul 2014

Zeng Liang, Fee Brian E, Rivas Miriam V, Lin James, Adamson David Cory

Abstract excerpt

In a broad range of human cancers 1p36 has been a mutational hotspot which strongly suggests that the loss of tumor suppressor activity maps to this genomic region during tumorigenesis. Adherens junctional associated protein-1 (AJAP1; also known as Shrew1) was initially discovered as a novel transmembrane protein of adherent junctions in epithelial cells. Gene profiling showed AJAP1 on 1p36 is frequently lost or...

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Share to Cell Adhesion Molecules
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

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Source

Identifiers

PMID: 24807315
DOI: 10.3892/ijo.2014.2425

Genes

AJAP1

Provenance

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