Article
Divergence of the expression and subcellular localization of CCR4-associated factor 1 (CAF1) deadenylase proteins in Oryza sativa.
Plant molecular biology - 1 Jul 2014
Chou Wei-Lun, Huang Li-Fen, Fang Jhen-Cheng, Yeh Ching-Hui, Hong Chwan-Yang, Wu Shaw-Jye, Lu Chung-An
Abstract excerpt
Deadenylation, also called poly(A) tail shortening, is the first, rate-limiting step in the general cytoplasmic mRNA degradation in eukaryotic cells. The CCR4-NOT complex, containing the two key components carbon catabolite repressor 4 (CCR4) and CCR4-associated factor 1 (CAF1), is a major player in deadenylation. CAF1 belongs to the RNase D group in the DEDD superfamily, and is a protein conserved through...
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