Article
Practical aspects of risk assessment in gastrointestinal stromal tumors.
Journal of gastrointestinal cancer - 1 Sept 2014
Jones R L
Abstract excerpt
INTRODUCTION: Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract, which are characterized in the majority of cases by activating mutations in KIT and platelet-derived growth factor receptor alpha (PDGFRA). The introduction of tyrosine kinase inhibitors has revolutionized the management of patients with metastatic GIST. However, complete surgical resection remains the...
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