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The Role of Epigenetics in the Fibrotic Processes Associated with Glaucoma

1 Jan 2014

Abstract excerpt

Glaucoma is an optic neuropathy that affects 60 million people worldwide. The main risk factor for glaucoma is increased intraocular pressure (IOP), this is currently the only target for treatment of glaucoma. However, some patients show disease progression despite well-controlled IOP. Another possible therapeutic target is the extracellular matrix (ECM) changes in glaucoma. There is an accumulation of ECM in the...

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PMID: 24800062
DOI: 10.1155/2014/750459

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