The genetic variation in monocarboxylic acid transporter 2 (MCT2) has functional and clinical relevance with male infertility.

doi:10.4103/1008-682X.124561

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Article

The genetic variation in monocarboxylic acid transporter 2 (MCT2) has functional and clinical relevance with male infertility.

Asian journal of andrology - 1 Jan 2000

Lee Jinu, Lee Dong Ryul, Lee Suman

Abstract excerpt

Monocarboxylic acid transporter 2 (MCT2) transports pyruvate and lactate outside and inside of sperms, mainly as energy sources and plays roles in the regulation of spermatogenesis. We investigated the association among genetic variations in the MCT2 gene, male infertility and MCT2 expression levels in sperm. The functional and genetic significance of the intron 2 (+28201A > G, rs10506398) and 3' untranslated...

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PMID: 24799634
DOI: 10.4103/1008-682X.124561
PMCID: PMC4215676

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