Article
Associations of host genetic variants on CD4⁺ lymphocyte count and plasma HIV-1 RNA in antiretroviral naïve children.
The Pediatric infectious disease journal - 1 Sept 2014
Qin Min, Brummel Sean, Singh Kumud K, Fenton Terence, Spector Stephen A
Abstract excerpt
BACKGROUND: CD4 T-lymphocyte (CD4) counts and HIV plasma RNA concentration (RNA) are 2 key HIV disease markers. The complex interplay between virus and host genetics may contribute to differences in viral set point and CD4 status. Determining the effects of host genetic variation on HIV disease markers is often complicated by the use of antiretroviral therapy. In this study, the association between genetic...
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