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Article

Streptococcus pyogenes polymyxin B-resistant mutants display enhanced ExPortal integrity.

Journal of bacteriology - 1 Jul 2014

Port Gary C, Vega Luis A, Nylander Andrew B, Caparon Michael G

Abstract excerpt

The ExPortal protein secretion organelle in Streptococcus pyogenes is an anionic phospholipid-containing membrane microdomain enriched in Sec translocons and postsecretion protein biogenesis factors. Polymyxin B binds to and disrupts ExPortal integrity, resulting in defective secretion of several toxins. To gain insight into factors that influence ExPortal organization, a genetic screen was conducted to select...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24794568
DOI: 10.1128/JB.01596-14
PMCID: PMC4097577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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