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Article

Frequency and Abundance of Alphaherpesvirus DNA in Human Thoracic Sympathetic Ganglia

1 May 2014

Abstract excerpt

Alphaherpesvirus reactivation from thoracic sympathetic ganglia (TSG) and transaxonal spread to target organs cause human visceral disease. Yet alphaherpesvirus latency in TSG has not been well characterized. In this study, quantitative PCR detected varicella-zoster virus (VZV), herpes simplex virus 1 (HSV-1), and HSV-2 DNA in 117 fresh TSG obtained postmortem from 15 subjects. VZV DNA was found in 76 (65%)...

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PMID: 24789785
DOI: 10.1128/jvi.01070-14

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