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Article

The importance of 8993C>T (Thr399Ile) TLR4 polymorphism in etiology of osteoporosis in postmenopausal women.

Ginekologia polska - 1 Mar 2014

Uzar Izabela, Mrozikiewicz Przemyslaw M, Bogacz Anna, Bartkowiak-Wieczorek Joanna, Wolski Hubert, Seremak-Mrozikiewicz Agnieszka, Drews Krzysztof, Kraśnik Witold, Kamiński Adam, Czerny Bogusław

Abstract excerpt

INTRODUCTION: Toll-like receptors (TLR) may play a key role in initiating cellular signaling pathways by increasing the levels of inflammatory cytokines which, cooperating with osteoclasts, influence bone turnover Numerous research articles focused on the genetic background of this condition, among others on polymorphic variants in TLR genes. The aim of the study was to examine the role of 20877G>A (Arg753GIn) in...

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Share to Toll-Like Receptor 2
Share to Adaptor Proteins, Signal Transducing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24783428
DOI: 10.17772/gp/1710

Genes

TLR4
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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