Article
Genetic variations in SLC3A2/CD98 gene as prognosis predictors in non-small cell lung cancer.
Molecular carcinogenesis - 1 Jun 2015
Guo Xu, Li Hongwei, Fei Fei, Liu Boya, Li Xiaofei, Yang Hushan, Chen Zhinan, Xing Jinliang
Abstract excerpt
Non-small cell lung cancer (NSCLC) is characterized by poor prognosis and only a few molecular markers may be potentially used to predict the risk of progression. This study aims to assess the effects of single nucleotide polymorphisms (SNPs) in the CD98 gene on prognosis of NSCLC patients. We genotyped three potential functional SNPs in CD98 gene using Sequenom iPLEX genotyping system in a cohort of 482 NSCLC...
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