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Article

Genetic variants in NPAS2 gene and clinical outcomes of resectable non-small-cell lung cancer.

Future oncology (London, England) - 1 Mar 2021

He Yiwei, Wang Gang, Wang Qian, Zhao Zheng, Gan Lu, Yang Shirong, Wang Yongxing, Guo Shanshan, An Jiaze, Zhang Jian, Zhang Zhaohui, Zhou Feng

Abstract excerpt

Background: A series of studies have demonstrated that NPAS2 plays a critical role in the development and progression of several cancers. However, the association between genetic variants in the NPAS2 gene and the clinical outcome of patients with non-small-cell lung cancer (NSCLC) has not been investigated. Methods: Six functional SNPs in NPAS2 were selected and genotyped using the Sequenom iPLEX genotyping...

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PMID: 33541123
DOI: 10.2217/fon-2020-0211

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