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Article

Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer.

Scientific reports - 30 Apr 2014

Yasunaga Masahiro, Matsumura Yasuhiro

Abstract excerpt

The treatment of colorectal cancer (CRC) might be improved by the identification of a signalling pathway that could be targeted with novel therapeutics. The results of this study indicate that the taurine transporter SLC6A6 is highly expressed in CRC cells compared with normal colonocytes. SLC6A6 knockdown (KD) attenuated cell survival and was accompanied by enhanced drug sensitivity to 5-fluorouracil (5-FU),...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Source

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Identifiers

PMID: 24781822
DOI: 10.1038/srep04852
PMCID: PMC4004982

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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