Article
Hypoxia-cultured mouse mesenchymal stromal cells from bone marrow and compact bone display different phenotypic traits.
Experimental cell research - 1 Feb 2021
Rossetti Rafaela, Rós Felipe Augusto, Souza Lucas Eduardo Botelho de, Maçonetto Juliana de Matos, Costa Péricles Natan Mendes da, Ferreira Fernanda Ursoli, Borges Josiane Serrano, Carvalho Julianne Vargas de, Morotti Nayara Patrícia, Kashima Simone, Covas Dimas Tadeu
Abstract excerpt
It has been suggested that the bone marrow microenvironment harbors two distinct populations of mesenchymal stromal cells (MSC), one with a perivascular location and other present in the endosteum. A better understanding of the biology of these MSC subsets has been pursued in order to refine its clinical application. However, most comparative characterizations of mouse MSC have been performed in normoxia. This...
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