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Article

Impaired cytokine responses in patients with cryopyrin-associated periodic syndrome (CAPS).

Clinical and experimental immunology - 1 Sept 2014

Haverkamp M H, van de Vosse E, Goldbach-Mansky R, Holland S M

Abstract excerpt

Cryopyrin-associated periodic syndrome (CAPS) is characterized by dysregulated inflammation with excessive interleukin (IL)-1β activation and secretion. Neonatal-onset multi-system inflammatory disease (NOMID) is the most severe form. We explored cytokine responses in 32 CAPS patients before and after IL-1β blocking therapy. We measured cytokines produced by activated peripheral blood monuclear cells (PBMCs) from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NLR Family, Pyrin Domain-Containing 3 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 24773462
DOI: 10.1111/cei.12361
PMCID: PMC4137857

Genes

CAPS
TNF
NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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