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Article

Zebrafish as model organisms for studying drug-induced liver injury.

British journal of clinical pharmacology - 1 Dec 2014

Vliegenthart A D Bastiaan, Tucker Carl S, Del Pozo Jorge, Dear James W

Abstract excerpt

Drug-induced liver injury (DILI) is a major challenge in clinical medicine and drug development. New models are needed for predicting which potential therapeutic compounds will cause DILI in humans, and new markers and mediators of DILI still need to be identified. This review highlights the strengths and weaknesses of using zebrafish as a high-throughput in vivo model for studying DILI. Although the zebrafish...

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Identifiers

PMID: 24773296
DOI: 10.1111/bcp.12408
PMCID: PMC4219854

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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