Article
A 3'UTR polymorphism of IL-6R is associated with Chinese pediatric tuberculosis.
BioMed research international - 1 Jan 2014
Shen Chen, Qi Hui, Sun Lin, Xiao Jing, Yin Qing-qin, Jiao Wei-wei, Wu Xi-rong, Tian Jian-ling, Han Rui, Shen A-dong
Abstract excerpt
BACKGROUND: IL-6 is a proinflammatory cytokine that plays a critical role in host defense against tuberculosis (TB). Genetic polymorphisms of IL-6 and its receptor IL-6R had been discussed in adult TB recently. However, their role in pediatric TB is still unclear. Due to the obvious differences i...
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