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Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology

25 Apr 2014

Abstract excerpt

Blood proteins and their complexes have become the focus of a great deal of interest in the context of their potential as biomarkers of Alzheimer's disease (AD). We used a SOMAscan assay for quantifying 1001 proteins in blood samples from 331 AD, 211 controls, and 149 mild cognitive impaired (MCI) subjects. The strongest associations of protein levels with AD outcomes were prostate-specific antigen complexed to...

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PMID: 24768341
DOI: 10.1016/j.jalz.2013.09.016

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