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Article

Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors.

Cancer genetics - 1 Apr 2014

Roth Jacquelyn J, Santi Mariarita, Rorke-Adams Lucy B, Harding Brian N, Busse Tracy M, Tooke Laura S, Biegel Jaclyn A

Abstract excerpt

Single nucleotide polymorphism (SNP) array analysis is currently used as a first tier test for pediatric brain tumors at The Children's Hospital of Philadelphia. The results from 100 consecutive patients are summarized in the present report. Eighty-seven percent of the tumors had at least one pathogenic copy number alteration. Nineteen of 56 low grade gliomas (LGGs) demonstrated a duplication in 7q34, which...

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Identifiers

PMID: 24767714
DOI: 10.1016/j.cancergen.2014.03.002
PMCID: PMC4161453

Genes

BRAF
CHEK2
MYB
QKI

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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