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Article

Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Nov 2014

LaDuca Holly, Stuenkel A J, Dolinsky Jill S, Keiles Steven, Tandy Stephany, Pesaran Tina, Chen Elaine, Gau Chia-Ling, Palmaer Erika, Shoaepour Kamelia, Shah Divya, Speare Virginia, Gandomi Stephanie, Chao Elizabeth

Abstract excerpt

PURPOSE: The aim of this study was to determine the clinical and molecular characteristics of 2,079 patients who underwent hereditary cancer multigene panel testing. METHODS: Panels included comprehensive analysis of 14-22 cancer susceptibility genes (BRCA1 and BRCA2 not included), depending on the panel ordered (BreastNext, OvaNext, ColoNext, or CancerNext). Next-generation sequencing and deletion/duplication...

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Source

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Identifiers

PMID: 24763289
DOI: 10.1038/gim.2014.40
PMCID: PMC4225457

Genes

BRCA1
BRCA2
EPCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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