Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Changes in aldehyde dehydrogenase-1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancer

24 Apr 2014

Abstract excerpt

INTRODUCTION: Although neoadjuvant chemotherapy (NAC) for locally advanced breast cancer can improve operability and local disease control, there is a lack of reliable biomarkers that predict response to chemotherapy or long-term survival. Since expression of aldehyde dehydrogenase-1 (ALDH1) is associated with the stem-like properties of self-renewal and innate chemoresistance in breast cancer, we asked whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer, Hypoxia, and Metabolism
Share to Cancer, Stress, Anesthesia, and Immune Response

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24762066
DOI: 10.1186/bcr3648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Changes in aldehyde dehydrogenase-1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancerPMID 24762066Read ↗

Aldehyde dehydrogenase 1 expression correlates with the invasion of breast cancer.Semantic proximity Read ↗

ALDH1A1 in breast cancer: A prospective target to overcome therapy resistance (Review)Semantic proximity Read ↗

Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44+ human breast cancer cellsSemantic proximity Read ↗

High expression of stem cell marker ALDH1 is associated with reduced BRCA1 in invasive breast carcinomas.Semantic proximity Read ↗

Neoadjuvant Chemotherapy in early-stage breast cancer: the trend over time and the impact on axillary management, A National Cancer Database AnalysisSemantic proximity Read ↗

Transcriptional Shift Identifies a Set of Genes Driving Breast Cancer ChemoresistanceSemantic proximity Read ↗

An increase in cancer stem cell population after primary systemic therapy is a poor prognostic factor in breast cancer.Semantic proximity Read ↗

Expression of aldehyde dehydrogenase 1 (ALDH1) is associated with basal-like markers and features of aggressive tumours in African breast cancer.Semantic proximity Read ↗

Markers of tumor-initiating cells predict chemoresistance in breast cancer.Semantic proximity Read ↗

A dormant sub-population expressing interleukin-1 receptor characterises anti-estrogen resistant ALDH+ breast cancer stem cellsSemantic proximity Read ↗

Aldehyde Dehydrogenase Activity Is a Biomarker of Primitive Normal Human Mammary Luminal CellsSemantic proximity Read ↗

Increased Expression of Interleukin-1 Receptor Characterizes Anti-estrogen-Resistant ALDH+ Breast Cancer Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.