Article
Association between cytotoxic and invasive Pseudomonas aeruginosa and clinical outcomes in bacterial keratitis.
JAMA ophthalmology - 1 Feb 2013
Borkar Durga S, Fleiszig Suzanne M J, Leong Chelsia, Lalitha Prajna, Srinivasan Muthiah, Ghanekar Avanti A, Tam Connie, Li Wing Y, Zegans Michael E, McLeod Stephen D, Lietman Thomas M, Acharya Nisha R
Abstract excerpt
OBJECTIVES: To determine whether cytotoxic and invasive Pseudomonas aeruginosa strains differentially influence clinical presentation, outcomes, or therapeutic response in bacterial keratitis. METHODS: Pseudomonas aeruginosa isolates from the National Eye Institute-funded Steroids for Corneal Ulcers Trial were subtyped as cytotoxic or invasive strains. The main outcome measure compared between the 2 subtypes was...
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