Article
Brugada syndrome in spinal and bulbar muscular atrophy.
Neurology - 20 May 2014
Araki Amane, Katsuno Masahisa, Suzuki Keisuke, Banno Haruhiko, Suga Noriaki, Hashizume Atsushi, Mano Tomoo, Hijikata Yasuhiro, Nakatsuji Hideaki, Watanabe Hirohisa, Yamamoto Masahiko, Makiyama Takeru, Ohno Seiko, Fukuyama Megumi, Morimoto Shin-Ichiro, Horie Minoru, Sobue Gen
Abstract excerpt
OBJECTIVE: The aim of this study was to clarify myocardial involvement and its clinical implications in subjects with spinal and bulbar muscular atrophy (SBMA), a neuromuscular disease affecting both neuronal and nonneuronal tissues. METHODS: Two independent cardiologists evaluated ECGs from a total of 144 consecutive subjects with SBMA. We performed immunohistochemical, immunoblot, and quantitative real-time PCR...
Topics
- Adult
- Aged
- Brugada Syndrome
- Electrocardiography
- Female
- Humans
- Male
- Middle Aged
- Muscular Disorders, Atrophic
- Mutation
- Myocardium