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Article

Next-generation sequencing: a change of paradigm in molecular diagnostic validation.

The Journal of pathology - 1 Sept 2014

Salto-Tellez Manuel, Gonzalez de Castro David

Abstract excerpt

Next-generation sequencing (NGS) is beginning to show its full potential for diagnostic and therapeutic applications. In particular, it is enunciating its capacity to contribute to a molecular taxonomy of cancer, to be used as a standard approach for diagnostic mutation detection, and to open new treatment options that are not exclusively organ-specific. If this is the case, how much validation is necessary and...

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Identifiers

PMID: 24756835
DOI: 10.1002/path.4365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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