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Article

The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer.

Nucleic acids research - 1 Jun 2014

Sharma Naomi L, Massie Charlie E, Butter Falk, Mann Matthias, Bon Helene, Ramos-Montoya Antonio, Menon Suraj, Stark Rory, Lamb Alastair D, Scott Helen E, Warren Anne Y, Neal David E, Mills Ian G

Abstract excerpt

In prostate cancer (PC), the androgen receptor (AR) is a key transcription factor at all disease stages, including the advanced stage of castrate-resistant prostate cancer (CRPC). In the present study, we show that GABPα, an ETS factor that is up-regulated in PC, is an AR-interacting transcriptio...

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Share to Androgen Receptor Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24753418
DOI: 10.1093/nar/gku281
PMCID: PMC4041454

Genes

ERG
ETV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24753418-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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