Article
Bioinformatics pipelines for targeted resequencing and whole-exome sequencing of human and mouse genomes: a virtual appliance approach for instant deployment.
PloS one - 1 Jan 2014
Li Jason, Doyle Maria A, Saeed Isaam, Wong Stephen Q, Mar Victoria, Goode David L, Caramia Franco, Doig Ken, Ryland Georgina L, Thompson Ella R, Hunter Sally M, Halgamuge Saman K, Ellul Jason, Dobrovic Alexander, Campbell Ian G, Papenfuss Anthony T, McArthur Grant A, Tothill Richard W
Abstract excerpt
Targeted resequencing by massively parallel sequencing has become an effective and affordable way to survey small to large portions of the genome for genetic variation. Despite the rapid development in open source software for analysis of such data, the practical implementation of these tools through construction of sequencing analysis pipelines still remains a challenging and laborious activity, and a major...
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