Exploring Histone Acetylation in Ischemic Stroke: The Role of CREBBP and CKAP4 as Key Biomarkers

Abstract excerpt

<title>Abstract</title> <p>Background Ischemic stroke (IS) is a serious cerebrovascular disease. Excessive acetylated protein levels are linked to neuronal resistance to ischemia, making histone acetylation regulatory-related biomarkers crucial for IS. Methods To identify differentially expressed genes (DEGs) in GSE16561, differential expression analysis (normal <italic>versus</italic> IS) was performed. Key mo...

Topics

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• Acute Ischemic Stroke Management
• Cardiac Fibrosis and Remodeling
• Intracerebral and Subarachnoid Hemorrhage Research
• Kruppel-like factors research
• Neuroinflammation and Neurodegeneration Mechanisms
• S100 Proteins and Annexins
• Signaling Pathways in Disease

Identifiers and source

Literature Corpus work

cee180b9-ffc1-554c-ab14-ef64ca88eb37

DOI

10.21203/rs.3.rs-6336853/v1