Article
Investigating inherent functional differences between human cardiac fibroblasts cultured from nondiabetic and Type 2 diabetic donors.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000
Sedgwick Bryony, Riches Kirsten, Bageghni Sumia A, O'Regan David J, Porter Karen E, Turner Neil A
Abstract excerpt
INTRODUCTION: Type 2 diabetes mellitus (T2DM) promotes adverse myocardial remodeling and increased risk of heart failure; effects that can occur independently of hypertension or coronary artery disease. As cardiac fibroblasts (CFs) are key effectors of myocardial remodeling, we investigated wheth...
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