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Article

A nutritional conditional lethal mutant due to pyridoxine 5'-phosphate oxidase deficiency in Drosophila melanogaster.

G3 (Bethesda, Md.) - 16 Apr 2014

Chi Wanhao, Zhang Li, Du Wei, Zhuang Xiaoxi

Abstract excerpt

The concept of auxotrophic complementation has been proposed as an approach to identify genes in essential metabolic pathways in Drosophila melanogaster. However, it has achieved limited success to date, possibly due to the low probability of finding mutations fit with the chemically defined profile. Instead of using the chemically defined culture media lacking specific nutrients, we used bare minimum culture...

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Identifiers

PMID: 24739647
DOI: 10.1534/g3.114.011130
PMCID: PMC4065258

Genes

PNPO

Variants

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