Article
Hypermethylation of the enolase gene (ENO2) in autism.
European journal of pediatrics - 1 Sept 2014
Wang Yu, Fang Yudan, Zhang Fengling, Xu Miao, Zhang Jingzhi, Yan Jingbin, Ju Weina, Brown W Ted, Zhong Nanbert
Abstract excerpt
UNLABELLED: It has been hypothesized that dysregulation of brain-expressed genes is the major predisposing underlying mechanism for autism. This dysregulation may be mediated by differential methylation of CpG sites within gene promoters, which could be candidate biomarkers and used for early clinical screening of autism. A total of 131 pairs of age- and sex-matched autistic and control subjects were recruited in...
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