Expression mechanisms of mir-486-5p and its host gene sANK1 in porcine muscle.

doi:10.1007/s11033-024-09773-2

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Article

Expression mechanisms of mir-486-5p and its host gene sANK1 in porcine muscle.

Molecular biology reports - 23 Jul 2024

Guo Xiaoping, Lan Ganqiu, Jiang Qinyang, Guo Yafen, Ouyang Yiqiang, Liang Jing, Zhang Mingyuan

Abstract excerpt

BACKGROUND: MiR-486-5p has been identified as a crucial regulator of the PI3K/AKT signalling pathway, which plays a significant role in skeletal muscle development. Its host gene, sANK1, is also essential for skeletal muscle development. However, the understanding of porcine miR-486-5p and sANK1 has been limited. METHODS AND RESULTS: In this study, PCR analyses revealed a positive correlation between the...

Topics

Animals
MicroRNAs
Swine
Muscle, Skeletal
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
Muscle Development
Cell Differentiation
Myoblasts
Gene Expression Regulation
Binding Sites
MyoD Protein
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 39042282
DOI: 10.1007/s11033-024-09773-2

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