Identification of Novel CD74-NRG2α Fusion From Comprehensive Profiling of Lung Adenocarcinoma in Japanese Never or Light Smokers.

doi:10.1016/j.jtho.2020.01.021

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Article

Identification of Novel CD74-NRG2α Fusion From Comprehensive Profiling of Lung Adenocarcinoma in Japanese Never or Light Smokers.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jun 2020

Kohsaka Shinji, Hayashi Takuo, Nagano Masaaki, Ueno Toshihide, Kojima Shinya, Kawazu Masahito, Shiraishi Yuichi, Kishikawa Satsuki, Suehara Yoshiyuki, Takahashi Fumiyuki, Takahashi Kazuhisa, Suzuki Kenji, Takamochi Kazuya, Mano Hiroyuki

Abstract excerpt

INTRODUCTION: Studies are yet to characterize the differences in molecular profiles of lung adenocarcinoma (LUAD) among divergent ethnic groups. Herein, we conducted comprehensive molecular profiling of LUAD in never or light smokers from Asia to discover novel targetable mutations and prognostic biomarkers of this distinct disease entity. METHODS: We analyzed 996 cases of Japanese LUAD and performed whole-exome...

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PMID: 32036070
DOI: 10.1016/j.jtho.2020.01.021

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